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Providence Health & Services Junior Bioinformatician in Santa Monica, California


Providence is calling a full time, day shift Junior Bioinformatician to Providence John Wayne Cancer Institute Santa Monica, CA.

In this position you will:

  • Be responsible for the analysis and computing support for cancer-related research including microarray and next generation sequencing (NGS) data (genomic, transcriptomic, epigenomic and proteomic) anaysis.


Required qualifications for this position include:

  • Bachelor’s Degree or higher in Biology, Bioinformatics, Computational Biology, or a related field. Masters and PhD strongly preferred.

  • Experience in processing and managing raw data generated from:

  • Expression, SNP, and DNA methylation microarrays.

  • Whole-genome and targeted (exome and/or gene panel) sequencing.

  • Transcriptomic (mRNA-seq and smRNA-seq) sequencing.

  • Epigenomic (Methyl-seq and ChIP-seq) sequencing.

  • Other Next Generation Sequencing (NGS) techniques

  • Experience with NGS data generated on Illumina sequencing instruments, including the HiSeq and MiSeq platforms.

  • Experience using open source genomic analysis tools including SAMtools, Picard, GATK, BWA, MuTect, BEDtools, VCFtools, among others.

  • Experience using open source tools for the annotation and interpretation of genomic variants, such as ANNOVAR, VEP, SnpEff, among others.

  • Experience in transcriptome analysis, including differential expression analysis using DESeq2, edgeR, limma, or similar.

  • Experience in and understanding of the organization and utilization of public databases such as The Cancer Genome Atlas (TCGA), Gene Expression Omnibus (GEO-NCBI), ENCODE project, ArrayExpress (EMBL-EBI) among others.

  • Experience working with large-scale NGS data in high performance cluster computing environments.

  • Experience in at least one of the following scripting languages: bash, Python, or Perl.

  • Knowledge of basic genetics & statistics.

  • Experience in statistical analyses using R/Bioconductor.

  • Unix/Linux system administration experience.

Preferred qualifications for this position include:

  • Experience using cloud computing platforms such as Amazon and/or Google.

  • Experience using Cancer Genomics Cloud (CGC) resources.

  • Knowledge of human genetics.

  • Knowledge of cancer and molecular biology.

  • Publications that demonstrate knowledge and application of genomic analyses.

About the hospital you will serve:

The John Wayne Cancer Institute at Providence Saint John’s Health Center is a cancer research institute dedicated to the understanding and curing of cancer in order to eliminate patient suffering worldwide. The Institute's mission is accomplished by conducting innovative research focused on biological mechanisms to provide new understandings of the cause, diagnosis, control, and cure of cancer; training the next generation of surgical scientists who study and treat cancer; and researching unique experimental treatment services to rapidly develop and test new forms of diagnosis and therapy in order to improve the quality of life and expected survival of those afflicted with cancer.

We offer a full comprehensive range of benefits - see our website for details

Our Mission

As expressions of God’s healing love, witnessed through the ministry of Jesus, we are steadfast in serving all, especially those who are poor and vulnerable.

About Us

Providence Health & Services is a not-for-profit Catholic network of hospitals, care centers, health plans, physicians, clinics, home health care and services guided by a Mission of caring the Sisters of Providence began over 160 years ago. Providence is proud to be an Equal Opportunity Employer. Providence does not discriminate on the basis of race, color, gender, disability, veteran, military status, religion, age, creed, national origin, sexual identity or expression, sexual orientation, marital status, genetic information, or any other basis prohibited by local, state, or federal law.

Schedule: Full-time

Shift: Day

Job Category: Research

Location: California-Santa Monica

Req ID: 225278